2024 Organic anion transporter protein

Organic anion transporter protein

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WitrynaNational Center for Biotechnology Information Witryna9 paź 2012 · Finally, organic anion transport by OAT10 (SLC22A13) was reported to be driven by exchange with dicarboxylates or hydroxyl ions, similar to OAT4; however, ... Melnikov S, Dinour D. Urinary organic anion transporter protein profiles in AKI. Nephrol Dial Transplant. 2012; 27:1387–95. doi: 10.1093/ndt/gfr541. [Google Scholar] …

SLCO2A1 Gene - GeneCards SO2A1 Protein SO2A1 Antibody

WitrynaThe SLCO1B1 gene provides instructions for making a protein called organic anion transporting polypeptide 1B1, or OATP1B1. This protein is found in liver cells; it … WitrynaView/Edit Human. Solute carrier organic anion transporter family member 1B1 is a protein that in humans is encoded by the SLCO1B1 gene. [3] [4] Pharmacogenomic research indicates that genetic variations in this gene are associated with response to simvastatin. [5] Clinical guidelines exist that can guide dosing of simvastatin based on … crunch virtual classes

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WitrynaOrganic anion transporters (OATs) are the secondary/tertiary active transporter proteins that regulate anion balance in the body. They are primarily expressed in the kidney … Witryna21 lis 2008 · Organic anion transporter OAT1 undergoes constitutive and protein kinase C-regulated trafficking through a dynamin- and clathrin-dependent pathway … WitrynaIn this study, we examined expression of organic anion transporter (OAT) 4 (SLC22A11), organic anion transporting polypeptide (OATP) 2B1 (SLCO2B1, OATP … marana chinese restaurants

Reduced Organic Anion Transporter Expression Is a Risk Factor for ...

Organic anion transporting polypeptide 2B1 and breast cancer

Witryna26 wrz 2011 · Organic anion transporters (OATs) are located on either the basolateral or the apical membrane of the proximal tubule cell and mediate the absorption and … WitrynaObjectives: Recent reports indicated that reduced SLC22A7 (a gene-encoding organic anion transporter 2) expression in noncancerous liver tissue predicts hepatocellular … marana commercial real estateWitryna11.2.3.1.3 Organic anion-transporting peptides. OATs and organic cation transporters (OCTs) are two of the major transporter families responsible for the absorption, distribution, and elimination of environmental xenobiotics, plant or animal toxins, and drugs. Although both transport systems have distinct substrate preferences, OAT is … crunch variationen

"Witryna24 paź 2024 · DOI: 10.3390/ijms20245303 Abstract Renal drug transporters such as the organic cation transporters (OCTs), organic anion transporters (OATs) and … " - Organic anion transporter protein

Organic anion transporter protein

organic anion transport protein - French translation – Linguee

WitrynaOfficial Symbol : Slco3a1 Official Name : solute carrier organic anion transporter family, member 3a1 EnsemblGene ID : Other Names : Anr1, androgen regulated protein 1, … Witryna30 cze 2024 · Both uptake and efflux drug transporters are involved in kidney toxicity of some drugs. Source: reprinted from basit, radi, vaidya, karasu, prasad, ©2024. MATE, multidrug and toxin extrusion; MRP, multidrug resistance–associated protein; OAT, organic anion transporter; OCT, organic cation transporter; SGLT, sodium …

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Witryna21 mar 2024 · SLCO2A1 (Solute Carrier Organic Anion Transporter Family Member 2A1) is a Protein Coding gene. Diseases associated with SLCO2A1 include Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive, 2 and Hypertrophic Osteoarthropathy, Primary, Autosomal Dominant.Among its related pathways are Transport of vitamins, … Witryna3 wrz 2024 · DTU Biosustain. +45 45 25 80 20. Scientists discover the secret behind some protein transporters’ superiority. One transporter, MAE1, can export organic acids out of yeast spending close-to-zero energy. Organic acids are utilized as building blocks for plastic and rubber, and the finding could become important in industrial …

Witrynamolecular mechanism for PSP transport from the blood into hepatocytes is unclear. In the present study, six human major hepatic uptake transporters expressed on the … Witryna29 mar 2024 · Predicted to enable sodium-independent organic anion transmembrane transporter activity and thyroid hormone transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. …

WitrynaThis review provides a survey of cloned organic cation transporters and tentative models that illustrate how different types of organic cation transporters, expressed … WitrynaOrganic anion transporters (OATs) are the secondary/tertiary active transporter proteins that regulate anion balance in the body. They are primarily expressed in …

Witryna29 mar 2024 · This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the …

WitrynaBackground & objectives: Organic anion transport protein 1B1 (OATP1B1) is a major transporter protein for bile salt uptake in the enterohepatic circulation of bile salts. … marana disc golf courseWitryna9 wrz 2016 · Our approach should provide novel mechanistic insights into the role of OAT1 and other drug transporters implicated in metabolic diseases like gout, … marana discount mallWitryna21 mar 2024 · SLCO2B1 (Solute Carrier Organic Anion Transporter Family Member 2B1) is a Protein Coding gene. Diseases associated with SLCO2B1 include Bronchiectasis 3 and Ileum Cancer.Among its related pathways are Statin Pathway - Generalized, Pharmacokinetics and Drug ADME.Gene Ontology (GO) annotations … crunchwrap supreme taco bell copycatWitryna18 paź 2024 · Organic anion transporter 1 (OAT1) is a drug transporter expressed on the basolateral membrane of the proximal tubule cells in kidneys. It plays an essential role in the disposition of numerous clinical therapeutics, impacting their pharmacological and toxicological properties. The activation of protein kinase C (PKC) is shown to … crunchy amaretti biscuitsWitryna9 lip 2024 · Organic anion transporting polypeptides (OATPs) are important transporter proteins that are expressed at the plasma membrane of cells, where they mediate the influx of endogenous and exogenous substances including hormones, natural compounds and many clinically important drugs. OATP1A2, OATP2B1, OATP1B1 … marana dog registrationWitrynaAbstract. 1. Organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 are polyspecific transporters that mediate the transport of organic acids into … marana clinic marana azWitryna9 cze 2010 · The mycotoxin, ochratoxin A (OTA), is thought to be responsible for Balkan endemic nephropathy. OTA accumulates in several tissues, especially in the kidneys … crunchy amaretti biscuits recipe